Please see the additional information and summary below:

ESET Product / FeatureARM Support / ConsiderationESET Reference
ESET Endpoint SecurityESET Endpoint Security supports ARM64-based processors. However, some features have limitations or are unavailable on ARM64, including Specialized Cleaner, Exploit Blocker, and Deep Behavioral InspectionESET Endpoint Security – System Requirements
ESET InspectWindows ARM and Linux ARM are currently not supported. ESET Inspect – Supported Operating Systems
Vulnerability & Patch ManagementWindows ARM devices are currently not supported for Vulnerability & Patch Management. ESET PROTECT – Vulnerability & Patch Management
ESET Full Disk EncryptionESET Full Disk Encryption does not support ARM processors on Windows. EFDE support is available for supported Apple Mac ARM64 devices, subject to ESET's system requirements. However, the same compatibility rules apply to the guest operating system. For example, ESET Full Disk Encryption for Windows is not supported on ARM and cannot be used on Windows virtualized on Apple ARM CPUs.
ESET Full Disk Encryption – Requirements and Supported Systems
ESET LiveGuard Advanced (ELGA)As confirmed by the ESET Team, ELGA is a cloud-based service. As long as the device is running a compatible operating system and a supported ESET application, ELGA can be used.ESET LiveGuard Advanced – Specifications and Supported Systems

Additional Information

The above information has been confirmed with the ESET Team and is also supported by the current ESET Online Help documentation.

In particular, ESET Endpoint Security lists ARM64-based processors as supported, while also documenting specific feature limitations for ARM64 devices.

For ESET LiveGuard Advanced, the ESET documentation confirms that it requires a supported ESET application to be installed and activated. ELGA is a cloud-based service, so the key requirement is that the endpoint is running a compatible ESET application and supported operating system.